The B-PEN database
and the research
Participate in a research programme
The use of Logipren is coupled with the development of a centralised prescription database. This data is completely anonymised (for both patient and prescriber) within the institutions, before being sent to the data warehouse.
The main aim is to provide neonatology departments with the compared results of their prescription practices (B-PEN research programme conducted by the University Hospital of La Réunion). Moreover, the database allows the development of other research programmes.
A Scientific Committee has been established, consisting of doctors and pharmacists from all relevant hospital wards, representatives from learned societies (SFN, SFPC) and research units(CEPOI, INSERM.
Several research topics are currently being studied: prescription of antibiotics, antifungals and analgesics, the exposure of newborns to parabens via drugs, etc. This research forms the subject of medical theses, science theses and publications in peer-reviewed journals.
Comparing prescription practices
The B-PEN database enables a regular comparison of prescription practices between care units.
A report is drafted each year containing the results from each unit and graphs comparing these results.
The comparison is anonymous: each care unit is given a number which is used for the results presented. Each unit knows their own number but not that of the other units.
The results are analysed by doctors and pharmacists from all the hospitals at an annual meeting. They guide the research implemented within the B-PEN database.
Ongoing research
- Mupirocin: Isabelle Ligi (AP-HM, University Hospital La Conception)
- Diuretics: Silvia Iacobelli (University Hospital of La Réunion, CEPOI*)
- Antihypertensive: Silvia Iacobelli (University Hospital of La Réunion, CEPOI*)
- Acid suppressive medications: Manon Tauzin (CHI Créteil)
- Preminut (nutrition for preterm infants with a GA < 32 weeks of amenorrhea): Jean-Bernard Gouyon (CEPOI*)
- Epoetin Beta: Roselyne Brat (CHR Orléans)
*Centre d’Etudes Périnatales de l’Océan Indien
Do not hesitate to contact us to participate or suggest research topics
Scientific articles
Postnatal corticosteroid exposure in very preterm infants : A french cohort study
Frontiers in Pharmacology, 2023
Iacobelli, S., Allamèle-Moutama, K., Lorrain, S., Gouyon, B., Gouyon, J. B., Bonsante, F., & Logipren Collaborative Working Group (2023).
Postnatal corticosteroid exposure in very preterm infants: A French cohort study. Frontiers in pharmacology, 14, 1170842.
Paraben exposure through drugs in the neonatal intensive care unit : a regional chohort study
Frontiers in Pharmacology, 2023
Iacobelli, S., Commins, M., Lorrain, S., Gouyon, B., Ramful, D., Richard, M., Grondin, A., Gouyon, J. B., & Bonsante, F. (2023).
Paraben exposure through drugs in the neonatal intensive care unit: a regional cohort study. Frontiers in pharmacology, 14, 1200521.
Frequencies, Modalities, Doses and Duration of Computerized Prescriptions for Sedative, Analgesic, Anesthetic and Paralytic Drugs in Neonates Requiring Intensive Care: A Prospective Pharmacoepidemiologic Cohort Study in 30 French NICUs From 2014 to 2020
Frontiers in Pharmacology, 2022
Tauzin, M., Gouyon, B., Hirt, D., Carbajal, R., Gouyon, J. B., Brunet, A. C., Ortala, M., Goro, S., Jung, C., & Durrmeyer, X. (2022).
Frequencies, Modalities, Doses and Duration of Computerized Prescriptions for Sedative, Analgesic, Anesthetic and Paralytic Drugs in Neonates Requiring Intensive Care : A Prospective Pharmacoepidemiologic Cohort Study in 30 French NICUs From 2014 to 2020. Frontiers in pharmacology, 13, 939869.
Copy the URL to download : https://www.logipren.com/wp-content/uploads/2022/07/2022.07.18_Article-antalgiques-M-Tauzin.pdf
Prescription of Aminoglycosides in 23 French Neonatal Intensive Care Units
Antibiotics, 2021
Martin-Mons, S., Gouyon, B., Lorrain, S., Abasse, S., Alexandre, C., Binson, G., Brat, R., Caeymaex, L., Couringa, Y., Desbruyeres, C., Meglio, M. D., Escourrou, G., Flamein, F., Flechelles, O., Girard, O., Kermorvant-Duchemin, E., Lapillonne, A., Lafon, C., Di Maio, M., Mazeiras, G., … Gouyon, J. B. (2021).
Prescription of Aminoglycosides in 23 French Neonatal Intensive Care Units. Antibiotics (Basel, Switzerland), 10(11), 1422.
Copy the URL to download : https://www.logipren.com/wp-content/uploads/2022/07/2021.11.21_Prescription-of-Aminoglycosides-in-23-French-Neonatal-Intensive-Care-units.pdf
Antibiotics prescription over three years in a French benchmarking network of 23 Level 3 Neonatal Wards
Frontiers in Pharmacology, 2020
Martin-Mons, S., Lorrain, S., Iacobelli, S., Gouyon, B., Gouyon, J. B., & B-PEN Study Group (2021).
Antibiotics Prescription Over Three Years in a French Benchmarking Network of 23 Level 3 Neonatal Wards. Frontiers in pharmacology, 11, 585018.
https://www.frontiersin.org/articles/10.3389/fphar.2020.585018/abstract
https://doi.org/10.3389/fphar.2020.585018
Drug exposure for PDA closure in France: a prospective, cohort-based, analysis
European journal of clinical pharmacology.2020
Iacobelli, S., Lorrain, S., Gouyon, B., Gambacorta, S., Laforgia, N., Gouyon, J. B., & Bonsante, F. (2020).
Drug exposure for PDA closure in France: a prospective, cohort-based, analysis. European journal of clinical pharmacology, 76(12), 1765–1772.
Characteristics of prescription in 29 Level 3 Neonatal Wards over a 2-year period (2017-2018). An inventory for future research
Public Library of Science one (Plos One),2019
Gouyon, B., Martin-Mons, S., Iacobelli, S., Razafimahefa, H., Kermorvant-Duchemin, E., Brat, R., Caeymaex, L., Couringa, Y., Alexandre, C., Lafon, C., Ramful, D., Bonsante, F., Binson, G., Flamein, F., Moussy-Durandy, A., Di Maio, M., Mazeiras, G., Girard, O., Desbruyeres, C., Mourdie, J., … Gouyon, J. B. (2019).
Characteristics of prescription in 29 Level 3 Neonatal Wards over a 2-year period (2017-2018). An inventory for future research. PloS one, 14(9), e0222667.
A Computer Prescribing Order Entry-Clinical Decision Support system designed for neonatal care: results of the 'preselected prescription' concept at the bedside
Journal of clinical pharmacy and therapeutics,2017
Gouyon, B., Iacobelli, S., Saliba, E., Quantin, C., Pignolet, A., Jacqz-Aigrain, E., & Gouyon, J. B. (2017).
A Computer Prescribing Order Entry-Clinical Decision Support system designed for neonatal care: results of the 'preselected prescription' concept at the bedside. Journal of clinical pharmacy and therapeutics, 42(1), 64–68.
SAS LogipremF Paris Branch
104 boulevard Auguste Blanqui
75013 Paris
SAS LogipremF Headquarters
27, Avenue du Dr Jean Marie Dambreville, Terre Sainte
97410 Saint-Pierre - La Réunion
